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Focus On: Microenvironment in Treatment Resistance
"Cellular crosstalk in the pancreatic cancer microenvironment"
Marina Pasca di Magliano, Ph.D.
Professor, Department of Surgery
UNIVERSITY OF MICHIGAN ANN ARBOR

"Roles of the extracellular matrix in chemoresistance"
Madeleine Oudin., Ph.D.
Assistant Professor of Biomedical Engineering
TUFTS UNIVERSITY

Seminar hosted by Cosimo Commisso, Ph.D.
Associate Professor
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

Part of the NCI-designated Cancer Center Seminar Series at Sanford Burnham Prebys Medical Discovery Institute

Mar 8, 2021 10:00 AM in Pacific Time (US and Canada)

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Speakers

Marina Pasca di Magliano, Ph.D.
Professor, General Surgery; Cell and Developmental Biolo @University of Michigan
Dr. Pasca di Magliano's research concentrates on the formation and progression of pancreatic cancer. Her laboratory studies how mutant Kras, the key oncogene that initiates formation of pancreatic cancer, regulates elements of the pancreatic cancer microenvironment. Recently, her work has focused on the role of inflammation and immune infiltration in pancreatic cancer, with the overarching goal to identify new ways to target this disease harnessing the body's own immune system.
Madeleine Oudin, Ph.D.
Assistant Professor, Biomedical Engineering @Tufts University
Dr. Oudin completed a Ph.D. in Neuroscience from King’s College London, UK, where she studied the regulation of neuronal cell migration. As a post-doctoral fellow in Prof. Frank Gertler’s lab at the Koch Institute for Integrative Cancer Research at MIT, her research was focused on understanding how metastasis, the dissemination of tumor cells throughout the body, occurs and how aggressive cells become resistant to current treatments. She started as an Assistant Professor at Tufts University in the department of Biomedical Engineering in 2018, where her lab is focused on understanding the mechanisms by which the tumor microenvironment contributes to cancer metastasis and resistance to drugs.